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Answer:
The paralyzing effect of curare is caused by its ability to block the action of acetylcholine at neuron-muscle synapses.
Explanation:
Curare -used by South American Indians to attack their enemies and hunting- is considered a poison, that really is a chemical agent with paralyzing, neurotoxic, activity on skeletal muscle.
Curare is extracted from various plants -including Strychnos toxifera and Anomospermum grandiflora- or synthesized as D-tubocurarine.
The effect of curare is on the nicotinic receptors found in the neuromotor plate.
- Acetylcholine binds to its receptor at the neuromuscular synapse to promote the opening of the sodium channels required by the muscle fiber to contract.
- The neurotoxin blocks the receptors, preventing the action of the neurotransmitter acetylcholine, which induces muscle paralysis.
High doses of the neurotoxin can cause death from respiratory paralysis.
Learn more:
Mechanism of action of curare https://brainly.com/question/6987263