Each wizarding governing body will be responsible for the concealment, care and control of all magical beasts, beings, and spirits dwelling within its territory's borders. Should any such creature cause harm to, or draw the notice of, the Muggle community, that nation's wizarding governing body will be subject to discipline by the International Confederation of Wizards.

Since the International Statute of Wizarding Secrecy was enacted in 1692, wizards and witches had hidden the existence of magic from Muggles.Thus, in the modern age, most Muggles believed magic to be nothing but a childish fantasy. Wizards and witches hid their world with Muggle-Repelling Charms, and if a Muggle witnessed a magical event or saw a magical creature such as a dragon, their memories were erased. Confundus Charms were also occasionally employed to encourage Muggles to ignore any magic they witnessed. Violations of the Statute of Secrecy were prosecuted by the Improper Use of Magic Office, and the Misuse of Muggle Artefacts Office tried to keep bewitched items away from Muggles.

The Muggle Liaison Office was a division of the Department of Magical Accidents and Catastrophes presumably responsible for wizard-Muggle relations.Given the lack of Muggle awareness of the wizarding world, in accordance with the International Statute of Wizarding Secrecy of 1692, it can be presumed that the Muggle Liaison Office fulfilled its duties in a very one-sided manner. Those who worked in Muggle Relations presumably worked with this office.