Mandrake is the common name of a number of plants in the Nightshade family, genus Mandragora. The roots often look like man or woman, or can be easily made to resemble them. The plant has been used in witchcraft for a long time. According to this literature, the plant shrieks in pain, when it is pulled from the ground.

The root and leaves are used to make medicine. People take European mandrake root for treating stomach ulcers, colic, constipation, asthma, hay fever, convulsions, arthritis-like pain (rheumatism), and whooping cough.